Products for Research Use Only

Nardosinone

CAT: 0013-GTR19159839-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19159839-01Size:200 mg
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Description
Nardosinone has inhibitory effect on Ang II-induced hypertrophy in H9c2 cells, might be mediated by targeting PI3K/Akt and MEK/ERK signaling pathways. Nardosinone could protect against the neuronal injury exposed to OGD, which may be relevant to the promotion of PKA and ERK signaling pathway. Nardosinone enhances staurosporine- or dbcAMP-induced neurite outgrowth from PC12D cells, probably by amplifying both the MAP kinase-dependent and -independent signaling pathways of dbcAMP and staurosporine. The enhancement of NGF-induced neurite outgrowth from PC12D cells by Nardosinone involves activation of a down-stream step of the MAP kinase-dependent cascade of NGF coupled with PKC.
CAS Number
23720-80-1
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 250 mg/mL (998.68 mM)
Smiles
CC1CCC=C2C1 (C3C (CC2=O) OOC3 (C) C) C
Molecular Formula
C15H22O3
Molecular Weight
250.33
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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