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Sobetirome

CAT: 0013-GTR19158271-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19158271-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Sobetirome is a selective agonist of thyroid hormone receptor β (TRβ) and binds selectively to TRβ-1 (EC50: 0.16 μM) . (In Vivo) :Sobetirome (GC-1) is a thyroid hormone receptor β (TRβ) - and liver uptake-selective agonist. Sobetirome (48 nmol/kg) reduces high-density lipoprotein (HDL) cholesterol and very low-density lipoprotein (VLDL) triglyceride levels in euthyroid Mice. Sobetirome reduces HDL cholesterol and triglyceride Levels in hypercholesterolemic mice. Sobetirome increases hepatic HDL receptors and stimulates bile acid synthesis in hypercholesterolemic mice. Treatment with 10x Sobetirome (GC-1) results in a gain of fat mass of only 21% (1.7 g), and treatment with 20x Sobetirome (GC-1) induces a decrease in fat mass of 20%.
CAS Number
211110-63-3
Product Name Alternative
QRX-431 | IACS-010759
Purity
>98% (HPLC)
Solubility
DMSO: 30 mg/mL (91.4 mM) ; Ethanol: 30 mg/mL
Smiles
CC (C) c1cc (Cc2c (C) cc (OCC (O) =O) cc2C) ccc1O
Molecular Formula
C20H24O4
Molecular Weight
328.4
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2- (4- (4-hydroxy-3-isopropylbenzyl) -35-dimethylphenoxy) acetic acid

Alternative Products

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A3828-10Sobetirome
A15241-100Sobetirome 100mg
A15241-200Sobetirome 200mg
A15241-25Sobetirome 25mg
A15241-5Sobetirome 5mg
A15241-10Sobetirome 10mg
A15241-1Sobetirome 1mg
HY-14823GSobetirome (GMP)
HY-14823R-01Sobetirome (Standard)
TRC-S810094-25MGSobetirome-D6

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