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Lerisetron

CAT: 0013-GTR19157938-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19157938-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lerisetron is an antagonist of serotonin type 3 (5-HT3) receptor, with antiemetic activity.showed a decrease in total clearance and distribution volume of the central compartment in old rats. The lerisetron free (unbound) fraction remained unchanged among the groups, and there were no significant differences in alpha (1) -acid glycoprotein levels. The concentration-effect relationship was best described by a sigmoid E (max) model. Since the drug concentration in plasma at half-maximal effect (EC (50) ) decreased in old rats, an increased sensitivity to the effect of lerisetron in old animals could be expected.
CAS Number
143257-98-1
Purity
>98% (HPLC)
Solubility
DMSO:53 mg/ml (181.27 mM)
Smiles
C (c1ccccc1) n1c (nc2ccccc12) N1CCNCC1
Molecular Formula
C18H20N4
Molecular Weight
292.38
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

Alternative Products

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HY-105090-01Lerisetron
A15501-100Lerisetron 100mg
A15501-50Lerisetron 50mg
A15501-5Lerisetron 5mg
A15501-2Lerisetron 2mg
HY-105090RLerisetron (Standard)
A15501-25Lerisetron 25mg
A15501-10Lerisetron 10mg
A15501-1Lerisetron 1mg
A15501-10mM-DLerisetron 10mM * 1mL in DMSO

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