Products for Research Use Only
RegisterLogin

CHLOROQUINE

CAT: 0013-GTR19156888-01Size: 1 gDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19156888-01Size:1 g
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Chloroquine is an autophagy and toll-like receptors (TLRs) inhibitor. Chloroquine is an antimalarial and anti-inflammatory agent widely used to treat malaria and rheumatoid arthritis. Chloroquine is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro with EC50 of 1.13 μM.Chloroquine suppressed matrix metalloproteinase (MMP) -2 and MMP-9 mRNA expression and protein activity, whereas MMP-13 mRNA expression and proteolytic activity were increased. Despite enhancing TLR9 mRNA expression, chloroquine suppressed TLR9 protein expression in vitro.Daily treatment of mice with intraperitoneal (i.p.) chloroquine (80 mg/kg/day) for 22 days, did not inhibit the growth of control siRNA or TLR9 siRNA MDA-MB-231 breast cancer cells.
CAS Number
54-05-7
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO:100 mg/mL (312.63 mM) ; Ethanol:100 mg/mL (312.63 mM; Need ultrasonic)
Smiles
CCN (CC) CCCC (C) Nc1ccnc2cc (Cl) ccc12
Molecular Formula
C18H26ClN3
Molecular Weight
319.87
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

Related Products

CatalogName
GTR19177001-01Chloroxine
GTR191675786-Chloropurine
GTR19157172-016-Chloropurine
GTR19167365-016-Chloropurine riboside
GTR191907522-Amino-6-chloropurine
GTR191528956-Chloropurine-riboside-5'-triphosphate
GTR191527646-Chloropurine-riboside-5'-monophosphate
GTR192081466-Chloropurine-riboside-5'-triphosphate
GTR192074836-Chloropurine-riboside-5'-monophosphate
GTR19229896-016-Chloropurine riboside-5'-triphosphate sodium

Alternative Products

CatalogName
BA1002-500Chloroquine
T83602-01(+) -Chloroquine
HY-W614112(-) -Chloroquine
MBS5825250(+)-Chloroquine
A8628-100Chloroquine diphosphate
CS-O-47498Chloroquine d5

Popular Products