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GI 254023X

CAT: 0013-GTR19155740-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19155740-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GI254023X is a potent MMP9 and ADAM10 inhibitor (IC50s: 2.5 and 5.3 nM) with 100-fold selectivity for the α-secretase ADAM10 over ADAM17 (TACE) . GI254023X can remarkably inhibit the proliferation and induce the apoptosis of H929 cells. Its mechanism may be associated with inbihition of Notch1 activation.
CAS Number
260264-93-5
Purity
>98% (HPLC)
Solubility
DMSO:100 mg/mL (255.43 mM; Need ultrasonic)
Smiles
O=C (N[C@H] (C (NC) =O) C (C) (C) C) [C@@H] ([C@@H] (N (C=O) O) C) CCCC1=CC=CC=C1
Molecular Formula
C21H33N3O4
Molecular Weight
391.5
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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A4436-5GI 254023X
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A15322-25GI 254023X 25mg
TRC-G377202-75MGGI 254023X-d3
A15322-50GI 254023X 50mg
A15322-1GI 254023X 1mg
A15322-100GI 254023X 100mg
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A15322-5GI 254023X 5mg
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