Products for Research Use Only
RegisterLogin

PGpG

CAT: 0013-GTR19152593Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19152593Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
The linear diguanylate pGpG is the first phosphodiesterase-catalyzed hydrolysis product of cylic di-GMP (c-diGMP) . C-diGMP has been identified as a novel second messenger in bacteria that triggers various physiological changes such as virulence gene expression or cell differentiation. The role of pGpG in c-diGMP signalling is under investigation.
CAS Number
33008-99-0
Product Name Alternative
P1- (5'-Guanosyl) -P2- (5'-guanosyl) - (3'→5') -diphosphate, Sodium salt
Purity
≥ 95% (HPLC)
Form
Solid; Color: white to off-white
Smiles
O[C@H]1[C@H] (n2cnc3c (=O) [nH]c (N) nc23) O[C@H] (COP (=O) (O) O) [C@H]1OP (=O) (OC[C@H]1O[C@@H] (n2cnc3c (=O) [nH]c (N) nc23) [C@H] (O) [C@@H]1O) O
Molecular Formula
C20H26N10O15P2
Molecular Weight
Theoretical MW: 708.43 g/mol (free acid) ; Detected MW: 708.11 g/mol (free acid)
Storage Conditions
Store at -20 °C
Notes
For research use only.
Applications Notes
Spectroscopic Propertie: λmax 252 nm, ε 25.0 L mmol-1 cm-1 (Tris-HCl, pH 7.5) .

Chemical Information

5'-O-phosphonoguanylyl-(3'->5')-guanosine

PGpG is a 5'-phospho-(3'->5')-dinucleotide. It is a conjugate acid of a pGpG(3-).

CAS Number33008-99-0
PubChem CID135566597
IUPAC Name[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-4-hydroxy-2-(phosphonooxymethyl)oxolan-3-yl] hydrogen phosphate
Molecular FormulaC20H26N10O15P2
Molecular Weight708.4
XLogP-7.8
Topological Polar Surface Area372
Hydrogen Bond Donor Count10
Hydrogen Bond Acceptor Count19
Rotatable Bond Count10
Heavy Atom Count47
Formal Charge0
Complexity1420
SMILES
C1=NC2=C(N1[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)O[C@@H]4[C@H](O[C@H]([C@@H]4O)N5C=NC6=C5N=C(NC6=O)N)COP(=O)(O)O)O)O)N=C(NC2=O)N
InChI
InChI=1S/C20H26N10O15P2/c21-19-25-13-7(15(34)27-19)23-3-29(13)17-10(32)9(31)5(43-17)1-42-47(39,40)45-12-6(2-41-46(36,37)38)44-18(11(12)33)30-4-24-8-14(30)26-20(22)28-16(8)35/h3-6,9-12,17-18,31-33H,1-2H2,(H,39,40)(H2,36,37,38)(H3,21,25,27,34)(H3,22,26,28,35)/t5-,6-,9-,10-,11-,12-,17-,18-/m1/s1
InChIKey
ZEHOHLFQOXAZHX-MHARETSRSA-N
Chemical Structure
2D Structure
2D structure of 5'-O-phosphonoguanylyl-(3'->5')-guanosine
CAS: 33008-99-0
CID: 135566597
Formula: C20H26N10O15P2
MW: 708.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight708.4
XLogP3-7.8
Hydrogen Bond Donor Count10
Hydrogen Bond Acceptor Count19
Rotatable Bond Count10
Exact Mass708.10543416
Monoisotopic Mass708.10543416
Topological Polar Surface Area372 Ų
Heavy Atom Count47
Formal Charge0
Complexity1420
Isotope Atom Count0
Defined Atom Stereocenter Count8
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19222599-01PGPC
GTR17694451PGP9.5/PGP9 Mouse Monoclonal Antibody
GTR17692555PGP9.5/PGP9 Rabbit Monoclonal Antibody
GTR17987285PgpC Antibody
GTR17987283PgpA Antibody
GTR17987074PgpB Antibody
GTR17987284PgpB Antibody
GTR17987075PgpC Antibody
GTR17986950PgpB Antibody
GTR18019401Pgp1 Antibody

Alternative Products

CatalogName
NU-534-1PGpG
T381225'-pGpG (sodium salt)
P 023-055'- Phosphoguanylyl- (3' −> 5') - guanosine (pGpG / 5'-p (rG) p (rG) ), sodium salt
MBS256636-015'-Phosphoguanylyl-(3'?>5')-guanosine (pGpG / 5'-p(rG)p(rG)), sodium salt

Popular Products