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GEP44

CAT: 0013-GTR19144723-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19144723-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GEP44 is a peptide-biased triple agonist targeting the glucagon-like peptide-1 receptor (GLP-1R), neuropeptide Y1 receptor (Y1-R), and neuropeptide Y2 receptor (Y2-R) . It induces GLP-1R-dependent insulin secretion in rat and human islets by offsetting the actions of Y1-R and GLP-1R agonism, controlled by Y1-R antagonists. Additionally, GEP44 enhances glucose uptake in muscle tissue through Y1-R mediation independent of insulin and significantly reduces food intake and body weight in diet-induced obese rat models. GEP44 is utilized in studies related to obesity and type 2 diabetes.
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Storage Conditions
-20°C
Notes
For research use only.

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