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IS4

CAT: 0013-GTR19145179-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19145179-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IS4 is a selective competitive antagonist of CXCR4, exhibiting an IC50 of 0.65 nM in THP-1 cells and 38.75 nM in Jurkat cells. It remains stable in serum and is non-cytotoxic. IS4 competes with CXCL12 for binding to CXCR4, thereby inhibiting CXCL12-induced intracellular Ca2+ release and cancer cell migration. This compound is applicable in research on the prevention of metastasis in conditions such as breast cancer, prostate cancer, and leukemia.
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery
Molecular Weight
1075.22
Storage Conditions
-20°C
Notes
For research use only.

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