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4-Allylcatechol

CAT: 0804-HY-N1887-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N1887-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
4-Allylcatechol (4-Allylpyrocatechol) is a xylan which has oral activity and can be isolated from the root of Piper taiwanense. 4-Allylcatechol has a strong inhibitory activity against collagen-induced platelet aggregation (IC50 = 5.3 μM) . In addition, 4-Allylcatechol has anti-tuberculosis activity against Mycobacterium tuberculosis H37Rv (MIC = 27.6 μg/mL) [1].
CAS Number
1126-61-0
Product Name Alternative
Hydroxychavicol; 4-Allylpyrocatechol
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Antibiotic; Bacterial; Interleukin Related; TNF Receptor
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis; Immunology/Inflammation
Field of Research
Cancer; Infection; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/4-Allylcatechol.html
Purity
98.60
Solubility
DMSO : ≥ 100 mg/mL
Smiles
OC1=CC=C(CC=C)C=C1O
Molecular Formula
C9H10O2
Molecular Weight
150.17
Precautions
H315, H319
References & Citations
[1]Chen S, et al. Neolignans and phenylpropanoids from the roots of Piper taiwanense and their antiplatelet and antitubercular activities[J]. Phytochemistry, 2013, 93: 203-209.|[2]Ng PL, et al. Piper betle leaf extract enhances the cytotoxicity effect of 5-fluorouracil in inhibiting the growth of HT29 and HCT116 colon cancer cells. J Zhejiang Univ Sci B. 2014 Aug;15 (8) :692-700.|[3]Annavarapu T, et al. Anti-inflammatory and antioxidant activities of 4-allylpyrocatechol and its derivatives with molecular docking and ADMET investigations[J]. Bulletin of the karaganda university chemistry series, 2022, 1 (105) : 50-59.|[4]Pandey A, et al. Hydroxychavicol inhibits immune responses to mitigate cognitive dysfunction in rats. J Neuroimmunol. 2010 Sep 14;226 (1-2) :48-58.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported