Menin, Human

• Description:

  Menin Protein is an endocrine tumor suppressor and transcriptional regulator. By binding to various transcription factors and signaling molecules, Menin Protein plays roles in activating or inhibiting gene transcription and regulating multiple signaling pathways such as TGFβ and Wnt in different tissues. Menin Protein is crucial in processes including cell growth, cell cycle, genomic stability, and bone development. Menin Protein, Human is a recombinant Menin protein expressed by E. coli without a tag[1][2][3].

• Product Name Alternative:

  Menin Protein, Human, Human, E. coli

• UNSPSC:

  12352202

• Type:

  Recombinant Proteins

• Assay Protocol:

  https://www.medchemexpress.com/cytokines/menin-protein-human.html

• Purity:

  97

• Molecular Formula:

  4221 (Gene_ID) O00255-1 (M1-L615) (Accession)

• Molecular Weight:

  Approximately 68 kDa

• References & Citations:

  [2]Matkar S, et al. Menin: a scaffold protein that controls gene expression and cell signaling. Trends Biochem Sci. 2013 Aug;38 (8) :394-402.|[3]Karnik SK, et al. Menin controls growth of pancreatic beta-cells in pregnant mice and promotes gestational diabetes mellitus. Science. 2007 Nov 2;318 (5851) :806-9.|[1]Balogh K, et al. Menin and its interacting proteins: elucidation of menin function. Trends Endocrinol Metab. 2006 Nov;17 (9) :357-64.

• Shipping Conditions:

  Dry ice

• Storage Conditions:

  Stored at -80°C for 1 year

• Scientific Category:

  Recombinant Proteins