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Recombinant Mouse PD-L1 Protein

CAT: 0013-GTR19125075-01Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR19125075-01Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Recombinant Mouse Programmed Cell Death 1 Ligand 1 is produced by our Mammalian expression system and the target gene encoding Phe19-Thr238 is expressed with a 6His tag at the C-terminus.
Product Name Alternative
Programmed cell death 1 ligand 1Cd274; programmed cell death 1 ligand 1; PD-L1; PDCD1 ligand 1; programmed death ligand 1; B7 homolog 1; B7-H1; CD274
UniProt
Q9EP73
Expression Region
Phe19-Thr238
Conjugation
Unconjugated
Tag
C-6His
Origin
Mouse
Field of Research
Immunology & Inflammation
Endotoxin
< 1 EU/μg as determined by LAL test.
Purity
SDS-PAGE: Greater than 95% as determined by reducing SDS-PAGE.
Bioactivity
ELISA: Immobilized Anti-Human PDL1 mAb-Fc (Cat#orb2993144) at 2μg/ml (100 μl/well) can bind Mouse PD-L1-His (Cat#orb2994459) .The ED50 of Mouse PD-L1-His (Cat#orb2994459) is 23.35 ng/ml.. BLI: Loaded Mouse PD-L1-His (Cat#orb2994459) on HIS1K Biosensor, can bind Anti-Human PDL1 mAb-Fc (Cat#orb2993144) with an affinity constant of -3 nM as determined in BLI assay. (Regularly tested)
Form
Lyophilized
Molecular Weight
Predicted: 25.6 KDa. Observed: 39-58 KDa, reducing conditions
Storage Conditions
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Notes
For research use only.
Preservative
0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

UniProtKB · Q9EP73

Programmed cell death 1 ligand 1

PD1L1_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
Q9EP73
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Cd274
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
PD-L1, PDCD1 ligand 1, Programmed death ligand 1
EC number
—
Processing
Precursor
Secondary accessions
—
Protein keywords

Technical term

3D-structureReference proteome

Biological process

Adaptive immunityImmunity

Cellular component

Cell membraneEndosomeMembrane

PTM

Disulfide bondGlycoproteinUbl conjugation

Domain

Immunoglobulin domainRepeatSignalTransmembraneTransmembrane helix

Molecular function

Receptor