Recombinant Mouse IL-2RA Protein

CAT: 0013-GTR19125051-01Size: 10 µgDry Ice: NoHazardous: No

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CAT#:0013-GTR19125051-01Size:10 µg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Recombinant Mouse Interleukin-2 Receptor Subunit Alpha is produced by our Mammalian expression system and the target gene encoding Glu22-Lys236 is expressed with a human IgG1 Fc tag at the C-terminus.

Product Name Alternative

CD25; IL-2 R alpha; IL2RA; CD25 antigen; IDDM10; IL-2 receptor subunit alpha; IL2R; IL-2R subunit alpha; IL-2-RA; IL2-RA; interleukin 2 receptor; alpha; interleukin-2 receptor subunit alpha; p55; TAC antigen; TCGFR

UniProt

P01590

Expression Region

Glu22-Lys236

Conjugation

Unconjugated

Tag

C-Fc

Origin

Mouse

Endotoxin

< 1 EU/μg as determined by LAL test.

Purity

SDS-PAGE: Greater than 95% as determined by reducing SDS-PAGE.

Bioactivity

BLI: Loaded Rat IL-2-His (Cat#orb3002341) on HIS1K Biosensor, can bind Mouse IL-2RA-Fc (Cat#orb2994437) with an affinity constant of 0.63 nM as determined in BLI assay. Loaded Human IL-2-His (Cat#orb3002442) on HIS1K Biosensor, can bind Mouse IL-2RA-Fc (Cat#orb2994437) with an affinity constant of 0.7 nM as determined in BLI assay. Loaded Biotinylated Human IL-2-His-Avi (Cat#orb2993791) on SA Biosensor, can bind Mouse IL-2RA-Fc (Cat#orb2994437) with an affinity constant of 1.18 nM as determined in BLI assay.

Form

Lyophilized

Molecular Weight

Predicted: 51.6 KDa. Observed: 60-90 KDa, reducing conditions

Storage Conditions

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Notes

For research use only.

Preservative

0.2 μm filtered solution of PBS, pH 7.4.

UniProtKB · P01590

Interleukin-2 receptor subunit alpha

IL2RA_MOUSE · Mus musculus

View on UniProt ↗

Primary accession: P01590
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: Il2ra
Protein existence: 2: Evidence at transcript level
Organism: Mus musculus (Mouse)
Taxonomy ID: 10090
Alternative names: IL-2 receptor subunit alpha, IL-2-RA, IL-2R subunit alpha, IL2-RA
EC number: —
Processing: Precursor
Secondary accessions: Q61731

Protein keywords

PTM

Disulfide bondGlycoprotein

Biological process

Immunity

Cellular component

Membrane

Molecular function

Receptor

Technical term

Reference proteome

Domain

RepeatSignalSushiTransmembraneTransmembrane helix

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