Recombinant Mouse NKG2D Protein

CAT: 0013-GTR19124888-01Size: 10 µgDry Ice: NoHazardous: No

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CAT#:0013-GTR19124888-01Size:10 µg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Recombinant Mouse NKG2-D Type II Integral Membrane Protein is produced by our Mammalian expression system and the target gene encoding Phe94 - Val232 is expressed with a human IgG1 Fc tag at the N-terminus.

Product Name Alternative

CD314; KLRK1; CD314 antigen; Killer cell lectin-like receptor subfamily K member 1; killer cell lectin-like receptor subfamily K; member 1; KLR; NK cell receptor D; NKG2-D; NKG2-D type II integral membrane protein; NKG2-D-activating NK receptor

UniProt

O54709

Expression Region

Phe94 - Val232

Conjugation

Unconjugated

Tag

N-Fc

Origin

Mouse

Field of Research

Immunology & Inflammation

Endotoxin

< 1 EU/μg as determined by LAL test.

Purity

SDS-PAGE: Greater than 95% as determined by reducing SDS-PAGE.

Bioactivity

ELISA: Immobilized Human MICA-Fc (Cat#orb2994621) at 10μg/ml (100 μl/well) can bind Mouse NKG2D-Fc* (Cat#orb2993888) *Biotinylated by NHS-biotin prior to testing. Immobilized Anti-Human NKG2D mAb (Cat#orb2993153) at 2μg/ml (100 μl/well) can bind Mouse NKG2D-Fc (Cat#orb2993888) .The ED50 of Mouse NKG2D-Fc (Cat#orb2993888) is 0.42ug/ml.. BLI: Loaded Mouse NKG2D-Fc (Cat#orb2993888) on Protein A Biosensor, can bind Human MICA-His (Cat#orb2995041) with an affinity constant of 0.42 uM as determined in BLI assay. (Regularly tested)

Form

Lyophilized

Molecular Weight

Predicted: 42.2 KDa. Observed: 45-60 KDa, reducing conditions

Storage Conditions

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Notes

For research use only.

Preservative

0.2 μm filtered solution of PBS, pH 7.4.

UniProtKB · O54709

NKG2-D type II integral membrane protein

NKG2D_MOUSE · Mus musculus

View on UniProt ↗

Primary accession: O54709
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: Klrk1
Protein existence: 1: Evidence at protein level
Organism: Mus musculus (Mouse)
Taxonomy ID: 10090
Alternative names: —
EC number: —
Processing: —
Secondary accessions: —

Protein keywords

Technical term

3D-structureReference proteome

Biological process

Adaptive immunityDifferentiationImmunityInnate immunity

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoprotein

Ligand

Lectin

Molecular function

Receptor

Domain

Signal-anchorTransmembraneTransmembrane helix

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