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Recombinant Human BCMA Protein

CAT: 0013-GTR19124639-01Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR19124639-01Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Recombinant Human Tumor Necrosis Factor Receptor Superfamily Member 17 is produced by our Mammalian expression system and the target gene encoding Met1-Ala54 is expressed with a mouse IgG1 Fc tag at the C-terminus.
Product Name Alternative
Tumor necrosis factor receptor superfamily member 17; B-cell maturation protein; CD269; Tnfrsf17; Bcm; Bcma
UniProt
Q02223
Expression Region
Met1-Ala54
Conjugation
Unconjugated
Tag
C-mFc
Origin
Human
Field of Research
Immunology & Inflammation
Endotoxin
< 1 EU/μg as determined by LAL test.
Purity
SDS-PAGE: Greater than 95% as determined by reducing SDS-PAGE.
Bioactivity
BLI: Loaded Mouse APRIL-Fc (Cat#orb2994771) on AHC Biosensor, can bind Human BCMA-mFc (Cat#orb2994062) with an affinity constant of -3 nM as determined in BLI assay. Loaded Human BAFF-Fc (Cat#orb2994098) on AHC Biosensor, can bind Human BCMA-mFc (Cat#orb2994062) with an affinity constant of 0.15 nM as determined in BLI assay. Loaded Human APRIL-His (Cat#orb2994084) on HIS1K Biosensor, can bind Human BCMA-mFc (Cat#orb2994062) with an affinity constant of 0.36 nM as determined in BLI assay.
Form
Lyophilized
Molecular Weight
Predicted: 32.5 KDa. Observed: 35-42 KDa, reducing conditions
Storage Conditions
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Notes
For research use only.
Preservative
0.2 μm filtered solution of PBS, pH 7.4.

UniProtKB · Q02223

Tumor necrosis factor receptor superfamily member 17

TNR17_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q02223
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TNFRSF17
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q2TQ40
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Biological process

Adaptive immunityImmunity

Coding sequence diversity

Alternative splicingChromosomal rearrangement

Cellular component

Cell membraneMembrane

PTM

Disulfide bond

Disease

Proto-oncogene

Molecular function

Receptor

Domain

Signal-anchorTransmembraneTransmembrane helix

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