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Recombinant Human ICOS Protein

CAT: 0013-GTR19124802-01Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR19124802-01Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Recombinant Human Inducible T-cell Costimulator is produced by our Mammalian expression system and the target gene encoding Glu21-Phe141 is expressed with a human IgG1 Fc tag at the C-terminus.
Product Name Alternative
Inducible T-cell costimulator; activation-inducible lymphocyte immunomediatory molecule; CD278; AILIM; CVID1; ICOS
UniProt
Q9Y6W8
Expression Region
Glu21-Phe141
Conjugation
Unconjugated
Tag
C-Fc
Origin
Human
Field of Research
Immunology & Inflammation
Endotoxin
< 1 EU/μg as determined by LAL test.
Purity
SDS-PAGE: Greater than 95% as determined by reducing SDS-PAGE.
Bioactivity
BLI: Loaded Recombinant Human ICOSLG (C-6His) (Cat#orb2995052) on HIS1K Biosensor, can bind Recombinant Human ICOS (C-Fc) (Cat#orb2994712) with an affinity constant of 9.56 nM as determined in BLI assay. (Regularly tested)
Form
Lyophilized
Molecular Weight
Predicted: 40.9 KDa. Observed: 47 KDa, reducing conditions
Storage Conditions
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Notes
For research use only.
Preservative
0.2 μm filtered solution of PBS, pH 7.4.

UniProtKB · Q9Y6W8

Inducible T-cell costimulator

ICOS_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9Y6W8
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ICOS
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
Q8N6W8
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembraneSecreted

PTM

Disulfide bondGlycoprotein

Domain

Immunoglobulin domainSignalTransmembraneTransmembrane helix

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