A2A receptor antagonist 1

• UNSPSC Description:

  A2A receptor antagonist 1 (CPI-444 analog) is an antagonist of both adenosine A2A receptor and A1 receptor with Ki values of 4 and 264 nM, respectively[1].

• Target Antigen:

  Adenosine Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/A2A_receptor_antagonist_1.html

• Purity:

  99.88

• Solubility:

  DMSO : 25 mg/mL (ultrasonic)

• Smiles:

  NC1=NC(C2=CC=CO2)=C3C(N(CC4=C(F)C=CC=C4)N=C3)=N1

• Molecular Weight:

  309.30

• References & Citations:

  [1]Gillespie RJ, et al. Antagonists of the human adenosine A2A receptor. Part 3: Design and synthesis of pyrazolo[3,4-d]pyrimidines, pyrrolo[2,3-d]pyrimidines and 6-arylpurines. Bioorg Med Chem Lett. 2008 May 1;18(9):2924-9.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  443103-97-7