Recombinant Human ETBR Protein

CAT: 0013-GTR19123785-01Size: 10 µgDry Ice: NoHazardous: No

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CAT#:0013-GTR19123785-01Size:10 µg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Recombinant Human Endothelin receptor type B is produced by our Mammalian expression system and the target gene encoding Glu27-Lys101 is expressed with a 6His tag at C-terminus.

Product Name Alternative

Endothelin receptor type B; EDNRB; ET-B; ET-BR; Endothelin receptor non-selective type; ETRB

UniProt

P24530

Expression Region

Glu27-Lys101

Tag

C-6His

Origin

Human

Endotoxin

< 1 EU/μg as determined by LAL test.

Purity

SDS-PAGE: Greater than 95% as determined by reducing SDS-PAGE. (QC verified)

Bioactivity

ELISA: Immobilized Recombinant Human ETBR N-ECD (C-6His) (Cat#orb2992706) at 2 μg/ml (100 μl/well) can bind Anti-Human ETBR mab (Human IgG1) . The ED50 of Anti-Human ETBR mab (Human IgG1) is 3.711 ng/ml. (Regularly tested)

Form

Lyophilized

Molecular Weight

Predicted: 8.9 KDa. Observed: 15- 33 KDa, reducing conditions

Storage Conditions

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Notes

For research use only.

Preservative

0.2 μm filtered solution of PBS, pH 7.4.

UniProtKB · P24530

Endothelin receptor type B

EDNRB_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P24530
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: EDNRB
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: ET-B, ET-BR
EC number: —
Processing: Precursor
Secondary accessions: A2A2Z8, A8K3T4, O15343, Q59GB1, Q5W0G9, Q8NHM6, Q8NHM7, Q8NHM8, Q8NHM9, Q9UD23, Q9UQK3

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Disease

AlbinismDeafnessDisease variantHirschsprung diseaseWaardenburg syndrome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoproteinLipoproteinPalmitatePhosphoprotein

Molecular function

G protein-coupled receptorReceptorTransducer

Domain

SignalTransmembraneTransmembrane helix

Related Products

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GTR18806922-01	Rat ETBR ELISA Kit
GTR18594907-01	DEDN6526A Biosimilar (ETBR Reference Antibody)
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Alternative Products

Catalog	Name
C44B-01	Recombinant Human ETBR (VLP)
C44C-01	Recombinant Human ETBR N-ECD (C-6His)
C44X-01	Recombinant Human ETBR N-ECD (C-Fc)
ARP2794-01	Recombinant Human Leptin Human Recombinant Protein
MBS1561940-01	Recombinant Human WAS protein
PPT-16033	Human WAS Recombinant Protein
TP727635	Human Recombinant Protein
E55A15834	Human ETBR Antibody
E55A07399	Human ETBR Antibody , FITC
E55A08406	Human ETBR Antibody , APC