Vindoline

• UNSPSC Description:

  Vindoline, a vinca alkaloid extracted from the leaves of Catharanthus roseus, weakly inhibits tubulin self-assembly[1].

• Target Antigen:

  Microtubule/Tubulin

• Type:

  Natural Products

• Related Pathways:

  Cell Cycle/DNA Damage;Cytoskeleton

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/vindoline.html

• Purity:

  99.50

• Solubility:

  DMSO : 250 mg/mL (ultrasonic)

• Smiles:

  CC[C@@]1(C=CCN2CC3)[C@@]2([H])[C@@]3(C4=CC=C(OC)C=C4N5C)[C@]5([H])[C@](C(OC)=O)(O)[C@@H]1OC(C)=O

• Molecular Weight:

  456.53

• References & Citations:

  [1]Prakash V, et al. Mechanism of interaction of vinca alkaloids with tubulin: catharanthine and vindoline. Biochemistry. 1991 Jan 22;30(3):873-80.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Clinical Information:

  No Development Reported

• CAS Number:

  2182-14-1