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Recombinant Human Complement factor D (CFD) (Active)

CAT: 0013-GTR19122693-01Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR19122693-01Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This Recombinant Human Complement factor D (CFD) (Active) spans the amino acid sequence from region 26-253aa. Purity: Greater than 95% as determined by SDS-PAGE.
Product Name Alternative
Complement factor D; EC:3.4.21.46; Adipsin; C3 convertase activator; Properdin factor D; CFD; DF, PFD
UniProt
P00746
Expression Region
26-253aa
Tag
C-terminal 10xHis-tagged
Source
Mammalian cell
Origin
Homo sapiens (Human)
Field of Research
Immunology & Inflammation
Endotoxin
Less than 1.0 EU/μg as determined by LAL method.
Purity
Greater than 95% as determined by SDS-PAGE.
Bioactivity
Measured by its binding ability in a functional ELISA. Immobilized Human CFD at 2 μg/mL can bind Anti-CFD recombinant antibody. The EC50 is 31.86-39.21 ng/mL.
Form
Lyophilized powder
Molecular Weight
25.9 kDa
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
For research use only.
Preservative
Lyophilized from a 0.2 μm filtered PBS, 6% Trehalose, pH 7.4
AA Sequence
ILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVLA

UniProtKB · P00746

Complement factor D

CFAD_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P00746
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CFD
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.4.21.46
Processing
Precursor
Secondary accessions
B4DV76, Q5U5S1, Q86VJ5, Q8N4E0, Q8WZB4
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Biological process

Complement alternate pathwayImmunityInnate immunity

Disease

Disease variant

PTM

Disulfide bondZymogen

Molecular function

HydrolaseProteaseSerine protease

Cellular component

Secreted

Domain

Signal

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