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Recombinant Human MHC class I polypeptide-related sequence B (MICB), partial (Active)

CAT: 0013-GTR19122692-01Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR19122692-01Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This Recombinant Human MHC class I polypeptide-related sequence B (MICB), partial (Active) spans the amino acid sequence from region 23-309aa. Purity: Greater than 95% as determined by SDS-PAGE.
Product Name Alternative
MHC class I polypeptide-related sequence B; MIC-B; MICB; PERB11.2
UniProt
Q29980
Expression Region
23-309aa
Tag
C-terminal 10xHis-tagged
Source
Mammalian cell
Origin
Homo sapiens (Human)
Field of Research
Cell Biology
Endotoxin
Less than 1.0 EU/μg as determined by LAL method.
Purity
Greater than 95% as determined by SDS-PAGE.
Bioactivity
Measured by its binding ability in a functional ELISA. Immobilized Human MICB at 2 μg/mL can bind Anti-MICA/B recombinant antibody. The EC50 is 1.087-1.369 ng/mL.
Form
Lyophilized powder
Molecular Weight
34.2kDa
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
For research use only.
Applications Notes
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Preservative
Lyophilized from a 0.2 μm filtered PBS, 6% Trehalose, pH 7.4
AA Sequence
AEPHSLRYNLMVLSQDESVQSGFLAEGHLDGQPFLRYDRQKRRAKPQGQWAEDVLGAKTWDTETEDLTENGQDLRRTLTHIKDQKGGLHSLQEIRVCEIHEDSSTRGSRHFYYDGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHYRAMQADCLQKLQRYLKSGVAIRRTVPPMVNVTCSEVSEGNITVTCRASSFYPRNITLTWRQDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSGNHGTHPVPSGKVLVLQSQRTD

UniProtKB · Q29980

MHC class I polypeptide-related sequence B

MICB_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q29980
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MICB
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
MIC-B
EC number
—
Processing
Precursor
Secondary accessions
A2AC57, A6NP85, B0UZ10, B2RAK2, O14499, O14500, O19798, O19799, O19800, O19801, O19802, O19803, O78099, O78100, O78101, O78102, O78103, O78104, P79525, P79541, Q5GR31, Q5GR37, Q5GR41, Q5GR42, Q5GR43, Q5GR44, Q5GR46, Q5GR48, Q5RIY6, Q5SSK1, Q5ST25, Q7JK51, Q7YQ89, Q861E6, Q9MY18, Q9MY19, Q9MY20, Q9UBH4, Q9UBZ8, Q9UEJ0, X6R344
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Biological process

Adaptive immunityCytolysisHost-virus interactionImmunity

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoprotein

Domain

Immunoglobulin domainSignalTransmembraneTransmembrane helix

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