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Recombinant Human Mesothelin (MSLN), partial, Biotinylated

CAT: 0399-CSB-MP015044HU-B-01Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0399-CSB-MP015044HU-B-01Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
(CAK1 antigen) (Pre-pro-megakaryocyte-potentiating factor) (MPF)
Abbreviation
Recombinant Human MSLN protein, partial, Biotinylated
Gene Name
MSLN
UniProt
Q13421
Expression Region
296-580aa
Organism
Homo sapiens (Human)
Target Sequence
EVEKTACPSGKKAREIDESLIFYKKWELEACVDAALLATQMDRVNAIPFTYEQLDVLKHKLDELYPQGYPESVIQHLGYLFLKMSPEDIRKWNVTSLETLKALLEVNKGHEMSPQVATLIDRFVKGRGQLDKDTLDTLTAFYPGYLCSLSPEELSSVPPSSIWAVRPQDLDTCDPRQLDVLYPKARLAFQNMNGSEYFVKIQSFLGGAPTEDLKALSQQNVSMDLATFMKLRTDAVLPLTVAEVQKLLGPHVEGLKAEERHRPVRDWILRQRQDDLDTLGLGLQG
Tag
N-terminal hFc-Avi-tagged
Type
In Stock Protein
Source
Mammalian cell
Field of Research
Cancer
Relevance
Membrane-anchored forms may play a role in cellular adhesion.; Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro.
Endotoxin
Not test
Purity
Greater than 90% as determined by SDS-PAGE.
Activity
Not Test
Form
Liquid or Lyophilized powder
Buffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Molecular Weight
61.4 kDa
References & Citations
"Humoral immune response to mesothelin in mesothelioma and ovarian cancer patients." Ho M., Hassan R., Zhang J., Wang Q.-C., Onda M., Bera T., Pastan I. Clin. Cancer Res. 11:3814-3820 (2005)
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Protein Length
Partial of Isoform 3

UniProtKB · Q13421

Mesothelin

MSLN_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q13421
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MSLN
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
D3DU65, Q14859, Q4VQD5, Q96GR6, Q96KJ5, Q9BR17, Q9BTR2, Q9UCB2, Q9UK57
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Cell adhesion

Cellular component

Cell membraneGolgi apparatusMembraneSecreted

PTM

Cleavage on pair of basic residuesDisulfide bondGlycoproteinGPI-anchorLipoproteinPhosphoprotein

Domain

Signal

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