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ML418

CAT: 0804-HY-122697-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-122697-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker. ML418 inhibits Kir7.1 with an IC50 value of 0.31 μM. ML418 can be used for the research of neurological, cardiovascular, endocrine and muscle disorders.
CAS Number
1928763-08-9
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Endocrinology; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ml418.html
Purity
99.78
Solubility
DMSO : 20.83 mg/mL (ultrasonic)
Smiles
O=C(OC(C)C)NC1CCN(CC2=CC(Cl)=C3C=CC=NC3=C2O)CC1
Molecular Formula
C19H24ClN3O3
Molecular Weight
377.87
Precautions
H302, H315, H319, H335
References & Citations
[1]ML418, et al. ML418: The First Selective, Sub-Micromolar Pore Blocker of Kir7.1 Potassium Channels. ACS Chem Neurosci. 2016 Jul 20;7 (7) :1013-23.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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