Cyclopentolate

• Description :

  Cyclopentolate (DL-Cyclopentolate) is an Atropine-like muscarinic receptors antagonist with a pKB value of 7.8 (on the circular ciliary muscle) . Cyclopentolate is an anti-muscarinic agent commonly used in the ophthalmologic practice[1][2].

• CAS Number :

  [512-15-2]

• Product Name Alternative :

  DL-Cyclopentolate

• UNSPSC :

  12352005

• Hazard Statement :

  H302-H315-H319-H335

• Target :

  MAChR

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/cyclopentolate.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CN(CCOC(C(C1(CCCC1)O)C2=CC=CC=C2)=O)C

• Molecular Formula :

  C17H25NO3

• Molecular Weight :

  291.39

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations :

  [1]Öner V, Bulut A, Öter K. The effect of topical anti-muscarinic agents on subfoveal choroidal thickness in healthy adults. Eye (Lond) . 2016;30 (7) :925‐928.|[2]Ishikawa H, DeSantis L, Patil PN. Selectivity of muscarinic agonists including (+/-) -aceclidine and antimuscarinics on the human intraocular muscles. J Ocul Pharmacol Ther. 1998;14 (4) :363‐373.|[3]Öner V, Bulut A, Öter K. The effect of topical anti-muscarinic agents on subfoveal choroidal thickness in healthy adults. Eye (Lond) . 2016;30 (7) :925‐928.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Launched