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DFMTI

CAT: 0804-HY-100404-01Size: 10 mM - 1 mLDry Ice: NoHazardous: No
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CAT#:0804-HY-100404-01Size:10 mM - 1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DFMTI can completely block the rmGlu1 L757V glutamate response. In vitro: DFMTI can completely block the rmGlu1 L757V glutamate response, although significantly higher concentrations were required to induce blockade. In vivo: DFMTI is efficacious in disrupting prepulse inhibition when dosed orally in rats. DFMTI exhibits a moderate decrease in human potency of approximately 3-fold when compared to rat, exemplified by DFMTI.
CAS Number
864864-86-8
Product Name Alternative
MK5435
UNSPSC
12352005
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/DFMTI.html
Concentration
10mM
Purity
99.04
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(N(C(C)C)C1)C2=C1C=C(C3=C(C)N(C4=CC=C(F)C=C4F)N=N3)C=C2
Molecular Formula
C20H18F2N4O
Molecular Weight
368.38
References & Citations
18
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MGluR1

Alternative Products

CatalogName
BA5592-1DFMTI
A20558-50DFMTI 50mg
A20558-5DFMTI 5mg
A20558-1DFMTI 1mg
A20558-100DFMTI 100mg
A20558-25DFMTI 25mg
A20558-10DFMTI 10mg
A20558-10mM-DDFMTI 10mM * 1mL in DMSO

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