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Meloside A

CAT: 0804-HY-N5124-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N5124-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Meloside A (Isovitexin 2''-O-glucoside) is a phenylpropanoid found in barley with antioxidant activity. Meloside A can inhibit cell apoptosis and ROS production. Meloside A can inhibit androgen receptor (AR) nuclear translocation and AR protein expression. Meloside A can reduce IL-6, TGF-β1 and DKK-1 levels. Meloside A can be used for the researches of inflammation and endocrinology, such as hair loss[1].
CAS Number
60767-80-8
Product Name Alternative
Isovitexin 2''-O-glucoside; Isovitexin 2''-O-β-D-glucoside
UNSPSC
12352005
Target
Androgen Receptor; Apoptosis; Interleukin Related; Reactive Oxygen Species (ROS) ; TGF-β Receptor
Type
Natural Products
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; TGF-beta/Smad; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Endocrinology; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/meloside-a.html
Purity
98.55
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C=C(C2=CC=C(O)C=C2)OC3=CC(O)=C([C@H]4[C@@H]([C@H]([C@@H]([C@@H](CO)O4)O)O)O[C@H]5[C@@H]([C@H]([C@@H]([C@@H](CO)O5)O)O)O)C(O)=C13
Molecular Formula
C27H30O15
Molecular Weight
594.52
References & Citations
[1]Park HJ, et al. Meloside A Protects Dermal Papilla Cells from DHT-Induced Damage via Androgen Receptor Modulation. Curr Issues Mol Biol. 2025 Jun 9;47 (6) :436.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
IL-6

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