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Recombinant Human IL-9 protein

CAT: 0772-CD01481-01Size: 2 µgDry Ice: NoHazardous: No
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CAT#:0772-CD01481-01Size:2 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Interleukin-9 (IL-9) is encoded by the IL9 gene and produced by T-cells and specifically by CD4+ helper cells. IL-9 was originally identified as a cytokine found in the conditioned medium of a human T cell leukemia virus type I (HTLVI) transformed T cell line. It functions through the IL-9 receptor, which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. IL-9 can support the growth of IL-2 independent and IL-4 independent helper T-cells. Human IL-9 has approximately 56 % amino acid sequence identity with Mouse IL-9. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.
CAS Number
9000-83-3
Molecular Weight
Approximately 14.1 kDa, a single non-glycosylated polypeptide chain containing 126 amino acids.