Products for Research Use Only
RegisterLogin

Recombinant Human OPG protein

CAT: 0772-CD01180Size: 10 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0772-CD01180Size:10 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Osteoprotegerin (OPG), also named osteoclastogenesis inhibitory factor (OCIF), and tumor necrosis factor receptor superfamily member 11B (TNFRSF11B), is a TNFRSF11B-encoded protein in humans. OPG is a 401 a.a. basic glycoprotein which comprises 7 structural domains. It is either a 60 kDa monomer or a 120 kDa dimer linked by disulfide bridges. OPG acts as a decoy receptor for the receptor activator of nuclear factor kappa B ligand (RANKL) and inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro and may also play a role in preventing arterial calcification. OPG has been applied to decrease bone resorption in women with postmenopausal osteoporosis and in patients with lytic bone metastases. Mature human OPG shares 86 %, 87 %, 92 %, 92 % and 88 % amino acid sequence identity with mouse, rat, equine, canine and bovine OPG, respectively.
CAS Number
9000-83-3
Molecular Weight
Approximately 19.7 kDa, a single non-glycosylated polypeptide chain containing 173 amino acids.

Related Products

CatalogName
E1558Hu-01Human Osteoprotegerin, OPG ELISA KIT
BT-MCA0960-01OPG Monoclonal Antibody
BT-MCA0961-01OPG Monoclonal Antibody
BT-AP06576-01OPG Polyclonal Antibody
E0110Mo-01Mouse Osteoprotegerin, OPG ELISA KIT
E0237Ch-01Chicken Osteoprotegerin, OPG ELISA KIT
E0650Po-01Porcine Osteoprotegerin, OPG ELISA KIT
E0350Rb-01Rabbit Osteoprotegerin, OPG ELISA KIT
E0462Ca-01Canine Osteoprotegerin, OPG ELISA KIT
E0263Ra-01Rat Osteoprotegerin, OPG ELISA KIT

Alternative Products

CatalogName
ARP2794-01Recombinant Human Leptin Human Recombinant Protein
MBS1561940-01Recombinant Human WAS protein
PPT-16033Human WAS Recombinant Protein
TP727635Human Recombinant Protein

Popular Products