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Recombinant Human Rb protein

CAT: 0772-CD01007Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0772-CD01007Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Rb encoded by the RB1 gene in humans, is expressed by retina and belongs to the etinoblastoma-associated protein family. The hole protein consists of 928 a.a. and the rHuRb fragment occupies sequence of 792-929 a.a.. Rb is a key regulator of entry into cell division that acts as a tumor suppressor. It has many functions, for example, promotes G0-G1 transition when phosphorylated by CDK3/cyclin-C, and acts as a transcription repressor of E2F1 target genes and so on. The rHuRb is the region that rich of modified residue like phosphothreonine and N6-acetyllysine.
CAS Number
9000-83-3
Molecular Weight
Approximately 16.5 kDa, a single non-glycosylated polypeptide chain containing 146 amino acids.

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