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Recombinant Mouse IL-36 Alpha

CAT: 0772-CD00360-01Size: 2 µgDry Ice: NoHazardous: No
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CAT#:0772-CD00360-01Size:2 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Interleukin-36 (IL-36) is a pro-inflammatory cytokine which plays an important role in the pathophysiology of several diseases. IL-36α, IL-36β, and IL-36γ (formerly IL-1F6, IL-1F8, and IL-1F9) are IL-1 family members that signal through the IL-1 receptor family members IL-1Rrp2 (IL-1RL2) and IL-1RAcP. IL-36α is mainly found in skin and lymphoid tissues, but also in fetal brain, trachea, stomach and intestine. It is expressed by monocytes, B and T cells. Notably, IL-36 alpha is the only novel IL-1 family member expressed on T-cells. Recombinant Mouse interleukin-36 alpha contains 160 amino acids residues which is a single non-glycosylated polypeptide. Specifically, mouse IL-36α shares 83 % a.a. sequence identity with rat IL-36α, 54-60 % with human, rabbit, equine and bovine IL-36α.
CAS Number
9000-83-3
Molecular Weight
Approximately 18. kDa, a single non-glycosylated polypeptide chain containing 16 amino acids.

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