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Recombinant Mouse IL-7 protein

CAT: 0772-CD00351-01Size: 2 µgDry Ice: NoHazardous: No
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CAT#:0772-CD00351-01Size:2 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Interleukin-7 (IL-7) is encoded by the IL7 gene in mouse and secreted by stromal cells in the red marrow and thymus. The protein signals through the IL-7 receptor, which is a heterodimer consisting of IL-7 receptor alpha and IL-2 receptor gamma chain. IL-7 stimulates the differentiation of hematopoietic stem cells into lymphoid progenitor cells and it can stimulate proliferation of B cells, T cells and NK cells. Mouse IL-7 has approximately 65 % and 88 % amino acid sequence identity with human and rat IL-7 and both proteins exhibit cross-species activity. IL-7 as an immunotherapy agent has been examined in many human clinical trials for various malignancies and during HIV infection.
CAS Number
9000-83-3
Molecular Weight
Approximately 14.9 kDa, a single non-glycosylated polypeptide chain containing 129 amino acids.