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Recombinant Rat IL-22 protein

CAT: 0772-CD00106-01Size: 2 µgDry Ice: NoHazardous: No
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CAT#:0772-CD00106-01Size:2 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
IL-22 is belonging to IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences, but they are dissimilar in their biological functions. Produced by T lymphocytes and dendritic cells, IL-10 contributes to the inflammatory response in vivo. IL-22 signals through CRF2-4 and IL-22. It along with IL-17 is rapidly produced by splenic LTi-like cells and can be also produced by Th17 cells and likely plays a role in the coordinated response of both adaptive and innate immune systems. Recombinant rat Interleukin-22 contains 146 amino acids and it has approximately 79 % and 92 % amino acid sequence identity with human and Mouse IL-22.
CAS Number
9000-83-3
Molecular Weight
Approximately16.6 kDa, a single non-glycosylated polypeptide chain containing 146 amino acids.