L-690330

CAT: 0804-HY-101075-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-101075-01Size:5 mg

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Description

L-690330 is a competitive inhibitor of inositol monophosphatase (IMPase) with Kis of 0.27 and 0.19 μM for recombinant human and bovine IMPase, 0.30 and 0.42 μM for human and bovine frontal cortex IMPase, respectively. L-690330 exhibits 10-fold more sensitive than mouse and rat IMPase[1].

CAS Number

142523-38-4

UNSPSC

12352005

Target

Phosphatase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/l-690330.html

Purity

99.52

Solubility

H2O : 66.67 mg/mL (ultrasonic)

Smiles

OC1=CC=C(OC(P(O)(O)=O)(P(O)(O)=O)C)C=C1

Molecular Formula

C8H12O8P2

Molecular Weight

298.12

References & Citations

[1]Atack JR, et al. In vitro and in vivo inhibition of inositol monophosphatase by the bisphosphonate L-690,330. J Neurochem. 1993 Feb;60 (2) :652-8.|[2]Cárdenas C, et al. Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2+ transfer to mitochondria.Cell. 2010 Jul 23;142 (2) :270-83.|[3]Shtein L, et al. The inositol monophosphatase inhibitor L-690,330 affects pilocarpine-behavior and the forced swim test.Psychopharmacology (Berl) . 2013 Jun;227 (3) :503-8.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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Alternative Products

Catalog	Name
T15685	L-690330
BL176912-01	L 690330
A12255-50	L-690330 50mg
A12255-25	L-690330 25mg
A12255-5	L-690330 5mg
T60820	L-690330 hydrate
A12255-10	L-690330 10mg
A12255-100	L-690330 100mg
A12255-10mM-D	L-690330 10mM * 1mL in DMSO
CCP1053-01	A-L-A-L

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