Products for Research Use Only
RegisterLogin

Adatanserin

CAT: 0804-HY-121053-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-121053-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Adatanserin (WY-50324) is a high affinity, selective and partial agonist for the 5-HT1A receptor with a Ki of 1 nM. Adatanserin is a moderate affinity 5-HT2 receptor antagonist with a Ki of 73 nM. Adatanserin shows significant anxiolytic and antidepressant activity in an animal conflict model[1][2].
CAS Number
127266-56-2
Product Name Alternative
WY-50324; SEB-324
UNSPSC
12352005
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/adatanserin.html
Smiles
O=C(NCCN1CCN(CC1)C2=NC=CC=N2)C34CC(CC(C4)C5)CC5C3
Molecular Formula
C21H31N5O
Molecular Weight
369.50
References & Citations
[1]M A Abou-Gharbia, et al. Synthesis and SAR of adatanserin: novel adamantyl aryl- and heteroarylpiperazines with dual serotonin 5-HT (1A) and 5-HT (2) activity as potential anxiolytic and antidepressant agents. |[2]A Singh, et al. Antidepressant-like activity of compounds with varying efficacy at 5-HT1A receptors. Neuropharmacology. 1993 Apr;32 (4) :331-40.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
5-HT1 Receptor; mLAG-3; α-1 microglobulin

Alternative Products

CatalogName
BUP03268-01Adatanserin
T29645-01Adatanserin hydrochloride

Popular Products