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SLP9101555

CAT: 0804-HY-150513-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-150513-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SLP9101555 (compound 14c) is a potent and selective SphK2 (sphingosine kinase 2) inhibitor (Ki=90 nM) with 200-fold selectivity over SphK1. SLP9101555 markedly decreases extracellular S1P (sphingosine 1-phosphate) levels[1].
UNSPSC
12352005
Target
SphK
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/slp9101555.html
Purity
99.40
Solubility
10 mM in DMSO
Smiles
N=C(N1[C@H](C2=NC(C3=CC=C(CCC4CCCCC4)C(C(F)(F)F)=C3)=NO2)CCC1)N.[H]Cl
Molecular Formula
C22H29ClF3N5O
Molecular Weight
471.95
References & Citations
[1]Srinath Pashikanti, et al. Sphingosine Kinase 2 Inhibitors: Rigid Aliphatic Tail Derivatives Deliver Potent and Selective Analogues. ACS Bio Med Chem Au 2022.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
SphK2

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CatalogName
T63047-01SLP9101555

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