Recombinant Human APRIL (TNFSF13)

• Description:

  A proliferation-inducing ligand (APRIL), also known as TNFSF13, is a member of the tumor necrosis factor (TNF) ligand superfamily. APRIL/TNFSF13 has been shown to play a role in protecting cells from undergoing apoptosis and promoting B cell development. Human APRIL Recombinant Protein is purified APRIL (TNFSF13) produced in yeast.

• Synonyms:

  Human ; April

• Label:

  ICT

• Type:

  Recombinant Protein

• Source:

  Yeast

• Sequence:

  AVLTQKQKKQ HSVLHLVPIN ATSKDDSDVT EVMWQPALRR GRGLQAQGYG VRIQDAGVYL LYSQVLFQDV TFTMGQVVSR EGQGRQETLF RCIRSMPSHP DRAYNSCYSA GVFHLHQGDI LSVIIPRARA KLNLSPHGTF LGFVKL (146)

• Assay Protocol:

  The Mouse IL-17A protein can be used in cell culture, as an IL-17A ELISA Standard, and as a Western Blot Control.

• Form:

  Lyophilized

• Shipping Conditions:

  Shipping: Ships at ambient temperature, Ships overnight (domestic), International Priority Shipping

• Storage Temperature:

  -20°C

• Notes:

  20% discount

• Calculated Molecular Weight:

  16.4 kDa

• Target Description:

  A proliferation-inducing ligand (APRIL), also known as TNFSF13, is a member of the tumor necrosis factor (TNF) ligand superfamily. Nineteen cytokine ligands have been identified as part of the TNF family on the basis of sequence, functional, and structural similarities. Family members include TNF beta (TNFSF1), TNF alpha (TNFSF2), Lymphotoxin beta (TNFSF3), OX40 Ligand (TNFSF4), CD40 Ligand (TNFSF5), Fas Ligand (TNFSF6), CD27 Ligand (TNFSF7), CD30 Ligand (TNFSF8), 4-1BB Ligand (TNFSF9), TRAIL (TNFSF10), TRANCE/RANKL (TNFSF11), TWEAK (TNFSF12), APRIL(TNFSF13), BAFF (TNFSF13B), LIGHT (TNFSF14), TL1A/VEGI (TNFSF15), and GITR Ligand (TNFSF18)., , The TNFSF13 ligand (APRIL) is expressed by macrophages and dendritic cells. APRIL/TNFSF13 has been shown to play a role in protecting cells from undergoing apoptosis and promoting B cell development.