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2-Phenylacetamide

CAT: 0804-HY-W018197-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W018197-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
2-Phenylacetamide is a estrogen-like compound that can be isolated from Lepidium apetalum seeds. 2-Phenylacetamide inhibits p38 MAPK signaling pathway, exhibits anti-inflammatory, antioxidant, anti-hypertensive, and anti-fibrosis effects. 2-Phenylacetamide is orally active[1][2].
CAS Number
103-81-1
UNSPSC
12352005
Hazard Statement
H301, H319
Target
Endogenous Metabolite; p38 MAPK; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Immunology/Inflammation; MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/2-phenylacetamide.html
Purity
99.92
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N)CC1=CC=CC=C1
Molecular Formula
C8H9NO
Molecular Weight
135.17
Precautions
H301, H319
References & Citations
[1]Zeng M, et al., 2-Phenylacetamide Isolated from the Seeds of Lepidium apetalum and Its Estrogen-Like Effects In Vitro and In Vivo. Molecules. 2018 Sep 7;23 (9) :2293.|[2]Yuan PP, et al., 2-phenylacetamide Separated from the seed of Lepidium apetalum Willd. inhibited renal fibrosis via MAPK pathway mediated RAAS and oxidative stress in SHR Rats. BMC Complement Med Ther. 2023 Jun 23;23 (1) :207.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite

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