Products for Research Use Only
RegisterLogin

2-Iodomelatonin

CAT: 0804-HY-101176-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-101176-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
2-Iodomelatonin is a potent agonist of melatonin receptor 1 (MT1) with a Ki value of 28 pM, it is more 5-fold selective for MT1 over MT2[1]. 2-iodomelatonin can be used to identify, characterize and localize melatonin binding sites in the brain and peripheral tissues[1].
CAS Number
93515-00-5
UNSPSC
12352005
Target
Melatonin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-iodomelatonin.html
Purity
99.04
Solubility
DMF : 30 mg/mL (ultrasonic; warming) |DMSO : 30 mg/mL (ultrasonic; warming) |Ethanol : 20 mg/mL (ultrasonic; warming)
Smiles
CC(NCCC1=C(I)NC2=C1C=C(OC)C=C2)=O
Molecular Formula
C13H15IN2O2
Molecular Weight
358.17
References & Citations
[1]Tomkinson A, et al. A murine IL-4 receptor antagonist that inhibits IL-4- and IL-13-induced responses prevents antigen-induced airway eosinophilia and airway hyperresponsiveness. J Immunol. 2001 May 1;166 (9) :5792-800.|[2]Wang X, et al. The melatonin MT1 receptor axis modulates mutant Huntingtin-mediated toxicity.J Neurosci. 2011 Oct 12;31 (41) :14496-507.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MT1

Related Products

CatalogName
HY-W011060-01Cryptand 2.2.2
HY-B1500-012,2,2-Trichloroethanol
HY-W0733142,2,2-Trifluoroethoxyamine (hydrochloride)
HY-N2048-012,2':5',2''-Terthiophene
HY-132268-01Cav 2.2 blocker 2
HY-B1500R-012,2,2-Trichloroethanol (Standard)
HY-W011060R-01Cryptand 2.2.2 (Standard)
HY-Z8487-012- (2-Chlorophenyl) -2-hydroxycyclohexanone
HY-W098021-012,2-Dimethoxy-2-phenylacetophenone
HY-20755-012,2,2-Trifluoro-N- (2-hydroxyethyl) acetamide

Alternative Products

CatalogName
B6428-102-Iodomelatonin
PC1003049-012,2,2-Trifluoroethyl 2,2,2-trichloroacetate
H 038-0012'- , 2''-, 2''', 2'''', 2''''', 2''''''- Hexadeoxy- 2'-, 2'', 2''', 2'''', 2''''', 2''''''- hexafluoro- cyclic hexaadenosine monophosphate (2',2'',2''',2'''',2''''',2''''''-Hexa-F-c-hexadAMP / cFA6), sodium salt
PC32719-012,2,2,2'-Tetrafluoroacetophenone
OR1009873-012,2,2,2-Ethylenedinitrilotetraethanol
290342-012,2,2-Trifluoroethyl 2,5-bis (2,2,2-trifluoroethoxy) benzoate
TRC-T790240-50MG2,2,2-Trifluoroethyl 2-Hydroxy-5-(2,2,2-trifluoroethoxy)benzoate
TRC-T790200-100MG2,2,2-Trifluoroethyl 2,5-Bis(2,2,2-trifluoroethoxy)benzoate

Popular Products