Human STEAP1 Full Length Protein, Twin-Strep, His Tag (Nanodisc)

• Background:

  Six-transmembrane epithelial antigen of the prostate 1 (STEAP1) is an integral membrane protein that is highly up-regulated on the cell surface of several human cancers, making it a promising therapeutic target to manage these diseases. It shares sequence homology with three enzymes (STEAP2-STEAP4) that catalyze the NADPH-dependent reduction of iron (III) . Taking into account its high specificity and overexpression in human cancers, STEAP1 is nowadays a promising candidate to be imposed as a therapeutic target.

• Description:

  Human STEAP1 Full Length Protein, Twin-Strep, His Tag (ST1-H5286) is expressed from human 293 cells (HEK293) . It contains AA Glu 2 - Leu 339 (Accession # Q9UHE8-1) .

• Specifications:

  This protein carries a twin strep tag at the N-terminus and a polyhistidine tag at the C-terminus. The protein has a calculated MW of 44.7 kDa.

• Accession Number:

  Q9UHE8-1

• Expression Region:

  Glu 2 - Leu 339

• Host:

  HEK293

• Target:

  STEAP1

• Conjugation:

  Unconjugated

• Tag:

  N-Twin-Strep & C-10xHis

• Stability:

  ● The product MUST be stored at -70°C or lower upon receipt; ● -70°C for 3 months under sterile conditions.

• Endotoxin:

  1.0 EU per μg

• Purity:

  90%

• Format:

  Liquid

• Buffer:

  20 mM HEPES, 150 mM NaCl, pH7.5

• Additives:

  Trehalose

• Molecular Weight:

  44.7 kDa

• Shipping Conditions:

  Dry ice

• Storage Conditions:

  -70°C

• Package Size:

  500ug*1

• Species:

  Human