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Aerothionin

CAT: 0804-HY-121349Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-121349Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Aerothionin is an antibiotic with potent antimicrobial efficacy against bacteria and fungi. Aerothionin exhibits antitumor efficacy against adrenal pheochromocytomas and extra-adrenal paragangliomas (PPGLs) [1][2].
CAS Number
28714-26-3
UNSPSC
12352005
Target
Antibiotic; Bacterial; Fungal
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/aerothionin.html
Solubility
10 mM in DMSO
Smiles
O[C@@H]1[C@@]2(C=C(C(OC)=C1Br)Br)CC(C(NCCCCNC(C3=NO[C@@]4([C@H](C(Br)=C(C(Br)=C4)OC)O)C3)=O)=O)=NO2
Molecular Formula
C24H26Br4N4O8
Molecular Weight
818.10
References & Citations
[1]Drechsel A, et al., Anti-Tumor Activity vs. Normal Cell Toxicity: Therapeutic Potential of the Bromotyrosines Aerothionin and Homoaerothionin In Vitro. Mar Drugs. 2020 May 1;18 (5) :236.|[2]Šimovičová M. Synthesis of aerothionin analogs as potential antimycobacterial agents[J]. 2021.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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CatalogName
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