FAS/CD95 Polyclonal Antibody

• Background:

  Fas (CD95/APO-1) is a transmembrane glycoprotein belonging to the tumor necrosis factor (TNF) receptor superfamily. It can mediate apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains, leading to the formation of the death-inducing signaling complex (DISC) . FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The molecular mass of native Fas is 38 kDa, the high molecular weight form (40-55 kDa) of Fas is due to glycosylation.

• Description:

  This is a FAS/CD95 Polyclonal antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  ALPS1A, APO 1, Apo 1 antigen, APT1, CD95, FAS, FAS/CD95, FAS1, FASLG receptor, FASTM, TNFRSF6

• Swiss Prot:

  P25445

• Reactivity:

  Human

• Immunogen:

  Recombinant Human FAS/CD95 protein expressed by? E.coli

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal antibody

• Applications:

  WB

• Purification Method:

  Antigen affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:250-1:500

• Buffer:

  PBS with 0.02% sodium azide,50% glycerol pH 7.4

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  12kDa

• Observed Molecular Weight:

  14kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG