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BAX Polyclonal Antibody

CAT: 0866-RD90740A-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0866-RD90740A-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.
Description
This is a BAX Polyclonal antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
Apoptosis regulator BAX, Bcl-2-like protein 4 (Bcl2-L-4), BAX, BCL2L4
Swiss Prot
Q07812
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant Human BAX Protein expressed by E.coli
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal antibody
Applications
WB
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:1000
Buffer
PBS with 0.02% sodium azide,50% glycerol pH 7.4
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
19kDa
Observed Molecular Weight
15kDa
Host or Source
Rabbit
Isotype
IgG

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