PKM2 Polyclonal Antibody

• Background :

  This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.

• Description :

  This is a PKM2 Polyclonal antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  Pyruvate kinase PKM, Cytosolic thyroid hormone-binding protein, Opa-interacting protein 3, Pyruvate kinase 2/3, Pyruvate kinase muscle isozyme, Threonine-protein kinase PKM2, Thyroid hormone-binding protein 1 (THBP1), PKM, OIP3, PK2, PK3, PKM2

• Swiss Prot :

  P14618

• Reactivity :

  Human

• Immunogen :

  Recombinant Human PKM2 Protein expressed by E.coli

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal antibody

• Applications :

  WB

• Purification Method :

  Antigen affinity purification

• Assay Type :

  Antibody

• Concentration :

  1mg/mL

• Dilution :

  WB 1:500-1:1000

• Buffer :

  PBS with 0.02% sodium azide,50% glycerol pH 7.4

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  24 kDa

• Observed Molecular Weight :

  24 kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG