SNCA Polyclonal Antibody

• Background:

  Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release.Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores.Mechanistically, acts by increasing local Ca2+ release from microdomains which is essential for the enhancement of ATP-induced exocytosis.Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs at presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DNAJC5.

• Description:

  This is a SNCA Polyclonal antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  SNCA, NACP, PARK1, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor

• Swiss Prot:

  P37840

• Reactivity:

  Human, mouse, Rat

• Immunogen:

  Recombinant Human SNCA protein expressed by E.coli

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:1000

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH 7.4

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  51 kDa

• Observed Molecular Weight:

  51 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG