PPY Polyclonal Antibody (Capture/Detector)

• Background:

  Pancreatic polypeptide (PP),36-amino acid peptide, may function as an important feedback inhibitor of pancreatic secretion after a meal. It arises from both islet and acinar cells of the pancreas. Release of PP by a meal, primarily protein, occurs in a biphasic manner. PP is a negative regulator of energy homeostasis that suppresses food intake and lowers body weight. Similar to other gastrointestinal-derived peptides, PP also modulates gastrointestinal motility and may be involved in the regulation of anxiety. PP, a robust anorexigenic hormone, effectively modulates food intake and energy homeostasis, thus potentially aiding anti-obesity therapeutics. PP is produced in pancreatic islets of Langerhans and released into the circulation after ingestion of a meal. Peripherally administered PP suppresses food intake and gastric emptying. On the other hand, central administration of PP elicits food intake and gastric emptying.

• Description:

  This is a PPY (Capture/Detector) Polyclonal antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  Pancreatic polypeptide prohormone, PH, Pancreatic polypeptide Y, Pancreatic polypeptide, Pancreatic icosapeptide, PPY, PNP

• Swiss Prot:

  P01298

• Reactivity:

  Human

• Immunogen:

  Recombinant Human PPY Protein expressed by E.coli

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal antibody

• Applications:

  ELISA

• Purification Method:

  Antigen affinity purification

• Assay Type:

  Antibody

• Dilution:

  2-8mg/ml (Cap),0.1-0.4mg/ml (Det)

• Buffer:

  Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  Rabbit IgG