Anti-MERS-CoV Nucleocapsid Protein Polyclonal Antibody

• Background:

  Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.

• Description:

  This is a Anti-MERS-CoV Nucleocapsid Protein Virus Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  Coronavirus NP, coronavirus Nucleocapsid, coronavirus Nucleoprotein, cov np, ncov NP, novel coronavirus Nucleoprotein, NP, Nucleocapsid, Nucleoprotein

• Reactivity:

  MERS-CoV

• Immunogen:

  A synthetic peptide corresponding to the center region of MERS-CoV (NCoV / Novel coronavirus) Nucleocapsid Protein (NP protein)

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Virus Antibody

• Applications:

  WB

• Purification Method:

  Antigen affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:1000-1:5000

• Buffer:

  0.2 μm filtered solution in PBS

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG