EIF4EBP1 Polyclonal Antibody

• Background:

  This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

• Description:

  This is a eIF4EBP1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  EIF4EBP1, 4E-BP1, 4EBP1, BP-1, PHAS-I, eukaryotic translation initiation factor 4E-binding protein 1

• Gene ID:

  1978

• Swiss Prot:

  Q13541

• Reactivity:

  Human

• Immunogen:

  Recombinant fusion protein of human Eif4ebp1

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IF

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  IF 1:50-1:200

• Buffer:

  PBS with 0.02% sodium azide,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  48kDa/55kDa

• Observed Molecular Weight:

  60KDa

• Host or Source:

  Rabbit

• Isotype:

  IgG