Sorbitol Dehydrogenase Polyclonal Antibody

• Background:

  Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]) . The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD (+) cofactor.

• Description:

  This is a Sorbitol Dehydrogenase Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  SORD, HEL-S-95n, SORD1

• Gene ID:

  6652

• Swiss Prot:

  Q00796

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human Sorbitol Dehydrogenase

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  44kDa

• Observed Molecular Weight:

  12KDa/25KDa/45-60KDa

• Host or Source:

  Rabbit

• Isotype:

  IgG