LPCAT3 Polyclonal Antibody

• Background:

  Lysophospholipid O-acyltransferase (LPLAT that catalyzes the reacylation step of the phospholipid remodeling process also known as the Lands cycle. Catalyzes transfer of the fatty acyl chain from fatty acyl-CoA to 1-acyl lysophospholipid to form various classes of phospholipids. Converts 1-acyl lysophosphatidylcholine (LPC into phosphatidylcholine (PC (LPCAT activity, 1-acyl lysophosphatidylserine (LPS into phosphatidylserine (PS (LPSAT activity and 1-acyl lysophosphatidylethanolamine (LPE into phosphatidylethanolamine (PE (LPEAT activity. Favors polyunsaturated fatty acyl-CoAs as acyl donors compared to saturated fatty acyl-CoAs. Has higher activity for LPC acyl acceptors compared to LPEs and LPSs. Can also transfer the fatty acyl chain from fatty acyl-CoA to 1-O-alkyl lysophospholipid or 1-O-alkenyl lysophospholipid with lower efficiency (By similarity. Acts as a major LPC O-acyltransferase in liver and intestine. As a component of the liver X receptor/NR1H3 or NR1H2 signaling pathway, mainly catalyzes the incorporation of arachidonate into PCs of endoplasmic reticulum (ER membranes, increasing membrane dynamics and enabling triacylglycerols transfer to nascent very low-density lipoprotein (VLDL particles.

• Description:

  This is a LPCAT3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  C3F, LPCAT, LPLAT 5, LPSAT, MBOAT5, OACT5, nessy, LPCAT3

• Gene ID:

  10162

• Swiss Prot:

  Q6P1A2

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human LPCAT3

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Observed Molecular Weight:

  49kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG