Evofosfamide

• Description :

  Evofosfamide (TH-302) is a hypoxia-activated proagent with IC50 of 10 μM and 1000 μM in hypoxia (N2) and normoxia (21% O2), respectively.

• Product Name Alternative :

  TH-302

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Apoptosis

• Type :

  Reference compound

• Related Pathways :

  Apoptosis

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/TH-302.html

• Purity :

  98.0

• Solubility :

  DMSO : 94 mg/mL (ultrasonic; warming) |H2O : 4.35 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  O=P(NCCBr)(OCC1=CN=C(N1C)[N+]([O-])=O)NCCBr

• Molecular Formula :

  C9H16Br2N5O4P

• Molecular Weight :

  449.04

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  18

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 3

• CAS Number :

  [918633-87-1]