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SLC7A11/xCT Polyclonal Antibody

CAT: 0866-RD90115A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD90115A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc (-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death.
Description
This is a SLC7A11/xCT Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
SLC7A11, CCBR1, xCT
Gene ID
23657
Swiss Prot
Q9UPY5
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human SLC7A11/xCT
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.05% proclin300,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
26kDa
Observed Molecular Weight
27kDa
Host or Source
Rabbit
Isotype
IgG

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